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How many people actually have COVID-19?          woman  who  transmitted  COVID-19  to  5  other  people
               The  number  of  COVID-19  cases  and  deaths  are   may have had an incubation time of 19 days.
            increasing  every  day,  so  these  numbers  are  a  moving
            target. As of March 11, 2020, the World Health Organization   What are the symptoms of COVID-19?
            has  officially  announced  that  COVID-19  is  a  global   What  is  important  to  remember  is  that  the  vast
            pandemic.                                        majority,  likely  over  80%,  of  infected  people  appear  to
               I  have  been  looking  at  the  global  Coronavirus   have mild infections – with mild cold-like symptoms and
            COVID-19 tracker from Johns Hopkins for accurate daily   fever, and likely many who have no symptoms. As noted
            numbers. which synthesizes data from 5 different sources:   above,  there  are  case  reports  of  asymptomatic  carriers.
            WHO, CDC, European Centre for Disease Prevention and   However, most people who contract COVID-19 do seem
            Control, China’s National Health Commission, and ncov.  to develop symptoms of some sort.
            dxy.cn, an independent data source maintained by Chinese   Reported symptoms include:
            physicians.
               ** In a way, the actual numbers don’t really matter.   •  Fever (which may not be present in the very young
            What matters is that we know that COVID-19 is here,   or very old, or immunocompromised)
            and that we do our best to stay calm & rationally   •  Uncomplicated upper respiratory symptoms
            prepared. I do not recommend checking numbers daily –   (Cough, sore throat, nasal congestion, malaise,
            that will only serve to heighten your anxiety. **    headache, muscle aches)
               As of March 12, 2020, there have been at least 127 863   •  Difficulty breathing
            global confirmed cases, 80 932 of which are in mainland   •  Mild pneumonia
            China.  The  rate  of  new  daily  cases  in  China  is  slowing   •  Severe pneumonia (the severe pneumonia caused
            down while the rate in other countries has been increasing.   by COVID-19 is now named severe acute
            Italy, Iran, and South Korea have the next highest number   respiratory infection (SARI))
            of  COVID-19  cases,  at  12  462,  10  075,  7869  cases   •  Acute Respiratory Distress Syndrome (ARDS)
            respectively. As of March 12, 2020, there are 1323 cases of   •  Sepsis and Septic shock
            confirmed COVID-19 in the US. 2                    •  Death
               Infection from exposure to COVID-19 from within the
            reporting country is far surpassing infection from exposure   Death is of course what we are all worried about. So
            due  to  travel  from  another  country,  with  an  increasing   let’s look at that a little more closely in the next section.
            number of infected persons with no history of international   What is interesting to note is that children seem less
            travel or close contact with a patient with known infection.   vulnerable to infection and appear to have milder symptoms
            Domestic  community  spread  is  becoming  an  increasing   than adults. There have been NO reported deaths in
            concern in the US and in other countries, and we need to   children 0-9 years of age. One very small study of 9 infants
            have more strategies for early detection, containment and   under 1 year of age infected with COVID-19 found that
            treatment than just closing our borders.         none of the infants had severe illness or complications. In
                                                             fact, 1 had no symptoms, 2 had mild upper respiratory tract
            How is COVID-19 transmitted?                     symptoms, and 4 had fever. 5
               It is now clear that human-to-human transmission of   Pregnant women also do not appear to be at greater
            COVID-19 is possible and is occurring. Transmission is   risk for complications. In a small study of 9 women in
            mainly  through  respiratory  droplets  and  close  contact–  Wuhan in their 3rd trimester of pregnancy with confirmed
            similar to how influenza is spread. The CDC defines close   and symptomatic COVID-19 infection, none  developed
            contact as being within 6 feet or within a room or care area   severe pneumonia or died. All gave birth via c-section to
            for  a  prolonged  period  without  personal  protective   healthy-appearing babies with normal Apgar scores. No
            equipment OR having direct contact with secretions of a   virus was found in amniotic fluid, cord blood or breastmilk. 6
            person with COVID-19 infection. There is some evidence
            that  fecal-oral  or  blood  transmission  may  be  possible,   What is the COVID-19  mortality rate?
            even  when  COVID-19  is  not  detected  in  oral  swabs.    Unfortunately, we don’t really know. As stated above,
                                                          3
            Investigation is underway to determine how long COVID-  we need real case numbers to know real death rates. The
            19  can  survive  on  various  surfaces  and  possibly  be   high number of deaths in China is devastating, but may
            transmitted through “fomites” (a fancy word for objects or   not be reflective of mortality rates in other parts of the
            materials  that  can  carry  infection,  such  as  tabletops,   world  given  the  tragic  lack  of  hospital  staff,  medical
            keyboards, clothes and utensils).                supplies, ICU beds, and test kits that China is facing. And
               The  incubation  period  is  thought  to  be  2-14  days,   this may similarly be the case in other countries like Iran.
            with a median incubation period of 4 days. Patients are   If we just look at our current numbers, the death rate
            thought to be most contagious when they are symptomatic.   appears to be quite high. The reported mortality rate is
            However,  a  recent  report   found  that  an  asymptomatic   highest  in  Italy  at  6.6%,  in  China  it  is  3.8%,  in  Iran
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            Song—Coronavirus Pediatrician's Perspective                     Integrative Medicine • Vol. 19, No. 2 • April 2020  29
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