Page 32 - IMCJ19s1

215. te Velthuis AJ, van den Worm SH, Sims AC, Baric RS, Snijder EJ, van Hemert MJ. Zn(2+) 251. Wintachai P, Kaur P, Lee RC, Ramphan S, Kuadkitkan A, Wikan N, et al. Activity of
inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores andrographolide against chikungunya virus infection. Sci Rep. 2015 Sep 18;5:14179.
block the replication of these viruses in cell culture. PLoS Pathog. 2010 Nov 252. Saxena RC, Singh R, Kumar P, Yadav SC, Negi MP, Saxena VS, et al. A randomized double
4;6(11):e1001176. blind placebo controlled clinical evaluation of extract of Andrographis paniculata
216. Zinc for the common cold. Cochrane Systematic Review (2013) 6. John Wiley and sons, (KalmCold) in patients with uncomplicated upper respiratory tract infection.
Ltd Phytomedicine. 2010 Mar;17(3-4):178-85.
217. Kitabayashi C, Fukada T, Kanamoto M, Ohashi W, Hojyo S, Atsumi T, et al. Zinc suppresses 253. Gabrielian ES, Shukarian AK, Goukasova GI, Chandanian GL, Panossian AG, Wikman G,
Th17 development via inhibition of STAT3 activation. Int Immunol. 2010 May;22(5):375- Wagner H. A double blind, placebo-controlled study of Andrographis paniculata fixed
86. combination Kan Jang in the treatment of acute upper respiratory tract infections including
218. Ogura H, Murakami M, Okuyama Y, Tsuruoka M, Kitabayashi C, Kanamoto M, et al. sinusitis. Phytomedicine. 2002 Oct;9(7):589-97.
Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 254. Thamlikitkul V, Dechatiwongse T, Theerapong S, Chantrakul C, Boonroj P, Punkrut W, et
induction. Immunity. 2008 Oct 17;29(4):628-36. al. Efficacy of Andrographis paniculata, Nees for pharyngotonsillitis in adults. J Med Assoc
219. Mocchegiani E, Costarelli L, Giacconi R, Cipriano C, Muti E, Tesei S, Malavolta M. Thai. 1991 Oct;74(10):437-42.
Nutrient-gene interaction in ageing and successful ageing. A single nutrient (zinc) and 255. Sheeja K, Kuttan G. Modulation of Natural Killer Cell Activity, Antibody-Dependent Cellular
some target genes related to inflammatory/immune response. Mech. Ageing Dev. 127, Cytotoxicity, and Antibody-Dependent Complement-Mediated Cytotoxicity by Andrographolide
517–525. in Normal and Ehrlich Ascites Carcinoma–Bearing Mice. Immunopharmacol Immunotoxicol.
220. Fujihara J, Yasuda T, Kimura-Kataoka K, Takinami Y, Nagao M, Takeshita H. Association 2006;28(3):443-57.
of SNPs in genes encoding zinc transporters on blood zinc levels in humans. Leg Med 256. Gupta S, Mishra KP, Ganju L. Broad-spectrum antiviral properties of andrographolide.
(Tokyo). 2018 Jan;30:28-33. Arch Virol. 2017 Mar;162(3):611-623.
221. Mocchegiani E, Romeo J, Malavolta M, Costarelli L, Giacconi R, Diaz LE, Marcos A. Zinc: 257. Parichatikanond W, Suthisisang C, et al. Study of anti-inflammatory activities of the pure
dietary intake and impact of supplementation on immune function in elderly. Age compounds from Andrographis paniculata (burm.f.) Nees and their effects on gene
(Dordr). 2013 Jun;35(3):839-60. expression. Int Immunopharmacol. 2010 Nov;10(11):1361-73.
222. Mariani E, Neri S, Cattini L, Mocchegiani E, Malavolta M, Dedoussis GV, et al. Effect of 258. Ellan K, Thayan R, Raman J, Hidari KIPJ, Ismail N, Sabaratnam V. Anti-viral activity of
Zinc Supplementation on Plasma IL-6 and MCP-1 Production and NK Cell Function in culinary and medicinal mushroom extracts against dengue virus serotype 2: an in-vitro
Healthy Elderly: Interactive Influence of +647 MT1a and -174 IL-6 Polymorphic Alleles. study. BMC Complement Altern Med. 2019 Sep 18;19(1):260.
Exp Gerontol . 2008 May;43(5):462-71. 259. Lim WZ, Cheng PG, Abdulrahman AY, Teoh TC. The identification of active compounds
223. Vaira LA, Salzano G, Deiana G, De Riu G. Anosmia and ageusia: common findings in in Ganoderma lucidum var. antler extract inhibiting dengue virus serine protease and its
COVID-19 patients. Laryngoscope. 2020 Apr 1. computational studies. J Biomol Struct Dyn. 2019 Oct 24:1-16.
224. Pisano M, Hilas O. Zinc and Taste Disturbances in Older Adults: A Review of the 260. Sato N, Zhang Q, Ma CM, Hattori M. Anti-human immunodeficiency virus-1 protease
Literature. Consult Pharm. 2016 May;31(5):267-70. activity of new lanostane-type triterpenoids from Ganoderma sinense. Chem Pharm Bull
225. Maggini, S.; Wintergerst, E.S.; Beveridge, S.; Hornig, D.H. Selected vitamins and trace (Tokyo). 2009 Oct;57(10):1076-80.
elements support immune function by strengthening epithelial barriers and cellular and 261. Donatini B. Control of oral human papillomavirus (HPV) by medicinal mushrooms,
humoral immune responses. Br. J. Nutr. 2007, 98, S29–S35. Trametes versicolor and Ganoderma lucidum: a preliminary clinical trial. Int J Med
226. Webb, A.L.; Villamor, E. Update: Effects of antioxidant and non-antioxidant vitamin Mushrooms. 2014;16(5):497-8.
supplementation on immune function. Nutr. Rev. 2007, 65, 181. 262. Zhang W, Tao J, Yang X, Yang Z, Zhang L, Liu H, et al. Antiviral effects of two Ganoderma
227. Bozonet, S.M.; Carr, A.C.; Pullar, J.M.; Vissers, M.C.M. Enhanced human neutrophil lucidum triterpenoids against enterovirus 71 infection. Biochem Biophys Res Commun.
vitamin C status, chemotaxis and oxidant generation following dietary supplementation 2014 Jul 4;449(3):307-12.
with vitamin C-rich SunGold kiwifruit.Nutrients 2015, 7, 2574–2588. 263. Kim YS, Eo SK, Oh KW, Lee C, Han SS. Antiherpetic activities of acidic protein bound
228. De la Fuente, M.; Ferrandez, M.D.; Burgos, M.S.; Soler, A.; Prieto, A.; Miquel, J. Immune polysacchride isolated from Ganoderma lucidum alone and in combinations with
function in aged women is improved by ingestion of vitamins C and E. Can. J. Physiol. interferons. J Ethnopharmacol. 2000 Oct;72(3):451-8.
Pharmacol. 1998, 76, 373–380. 264. Xu Z1, Chen X, Zhong Z, Chen L, Wang Y. Ganoderma lucidum polysaccharides:
229. Carr, AC.; Maggini,S. Vitamin C and Immune Function Nutrients 2017, 9(11), 1211 immunomodulation and potential anti-tumor activities. Am J Chin Med. 2011;39(1):15-27.
230. Marik PE. Vitamin C for the treatment of sepsis: The scientific rationale. Pharmacol Ther. 265. Sun LX, Li WD, Lin ZB, Duan XS, Li XF, Yang N, et al. Protection against lung cancer
2018 Sep;189:63-70. patient plasma-induced lymphocyte suppression by Ganoderma lucidum polysaccharides.
231. Levine, M.; Dhariwal, K.R.; Welch, R.W.; Wang, Y.; Park, J.B. Determination of optimal Cell Physiol Biochem. 2014;33(2):289-99.
vitamin C requirements in humans. Am. J. Clin. Nutr. 1995, 62, 1347S–1356S. 266. Gao Y, Zhou S, Jiang W, Huang M, Dai X. Effects of ganopoly (a Ganoderma lucidum
232. Carr, A.C.; Frei, B. Toward a new recommended dietary allowance for vitamin C based on polysaccharide extract) on the immune functions in advanced-stage cancer patients.
antioxidant and health effects in humans. Am. J. Clin. Nutr. 1999, 69, 1086–1087. Immunol Invest. 2003 Aug;32(3):201-15.
233. Hemilä H. Vitamin C and infections. Nutrients 2017;9(4):E339. 267. Tsai CC, Yang FL, et al. Oligosaccharide and peptidoglycan of Ganoderma lucidum activate
234. Webb AL, Villamor E. Update: effects of antioxidant and non‐antioxidant vitamin the immune response in human mononuclear cells. J Agric Food Chem. 2012
supplementation on immune function. Nutrition Reviews 2007; Vol. 65, issue 5:181‐217. Mar21;60(11):2830-7.
235. May JM, Harrison FE. Role of vitamin C in the function of the vascular endothelium. 268. Chang CJ, Chen YY, Lai HC, et al. Ganoderma lucidum stimulates NK cell cytotoxicity by
Antioxid Redox Signal. 2013 Dec 10;19(17):2068-83. inducing NKG2D/NCR activation and secretion of perforin and granulysin. Innate Immun.
236. Fowler AA 3rd, Truwit JD, Hite RD, Morris PE, DeWilde C, Priday A, et al. Effect of 2014 Apr;20(3):301-11.
vitamin C infusion on organ failure and biomarkers of inflammation and vascular injury 269. Pi CC, Chu CL, Lu CY, Zhuang YJ, Wang CL, Yu YH, et al. Polysaccharides from
in patients with sepsis and severe acute respiratory failure: the CITRIS-ALI randomized Ganoderma formosanum function as a Th1 adjuvant and stimulate cytotoxic T cell
clinical trial. JAMA. 2019;322(13):1261–70. response in vivo. Vaccine. 2014 Jan 9;32(3):401-8.
237. ClinicalTrials.gov [internet] Bethesda (MD): National Library of Medicine (US) Identifier: 270. Lin YL1, Lee SS, Hou SM, Chiang BL. Polysaccharide purified from Ganoderma lucidum
NCT04264533, Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected induces gene expression changes in human dendritic cells and promotes T helper 1
Pneumonia. 2020, Feb 11. immune response in BALB/c mice. Mol Pharmacol. 2006 Aug;70(2):637-44.
238. Chu W. Hospital turns to high-dose vitamin C to fight coronoavirus. [internet] 03-26-20. 271. Lin CH, Hsiao YM, Ou CC, Lin YW, Chiu YL, Lue KH, et al. Ganoderma immunomodulatory
239. Hemilä H. Chalker, E. Vitamin C Can Shorten the Length of Stay in the ICU: A Meta- protein, down-regulates tumor necrosis factor α-induced expression of matrix
Analysis. Nutrients 2019, 11, 708. metalloproteinase 9 via NF-κB pathway in human alveolar epithelial A549 cells. J Agric Food
240. Dabbagh-Bazarbachi H, Clergeaud G, Quesada IM, et al. Zinc ionophore activity of Chem. 2010 Nov 24;58(22):12014-21.
quercetin and epigallocatechin-gallate: from Hepa 1-6 cells to a liposome model. J Agric 272. Batbayar S, Kim MJ, Kim HW. Medicinal mushroom Lingzhi or Reishi, Ganoderma
Food Chem. 2014 Aug 13;62(32):8085-93. lucidum beta‐glucan induces Toll‐like receptors and fails to induce inflammatory cytokines
241. Chiow KH, Phoon MC, Putti T, Tan BK, Chow VT. Evaluation of antiviral activities of in NF‐kappaB inhibitor‐treated macrophages. Int J Med Mushrooms. 2011;13(3):213‐225.
Houttuynia cordata Thunb. extract, quercetin, quercetrin and cinanserin on murine 273. Varghese FS, Thaa B, Amrun SN, Simarmata D, Rausalu K, Nyman TA, et al. The Antiviral
coronavirus and dengue virus infection. Asian Pac J Trop Med. 2016 Jan;9(1):1-7. Alkaloid Berberine Reduces Chikungunya Virus-Induced Mitogen-Activated Protein Kinase
242. Jo S, Kim H, Kim S, Shin DH, Kim MS. Characteristics of flavonoids as potent MERS-CoV Signaling. J Virol. 2016 Oct 14;90(21):9743-9757.
3C-like protease inhibitors. Chem Biol Drug Des. 2019 Dec;94(6):2023-2030 274. Wang J, Wang L, Lou GH, Zeng HR, Hu J, Huang QW, et al. Coptidis Rhizoma: a
243. Smith M, Smith JC. Repurposing Therapeutics for COVID-19: Supercomputer-Based comprehensive review of its traditional uses, botany, phytochemistry, pharmacology and
Docking to the SARS-CoV-2 Viral Spike Protein and Viral Spike Protein-Human ACE2 toxicology. Pharm Biol. 2019 Dec;57(1):193-225.
Interface. ChemRxiv. Preprint. 275. Varghese FS, Kaukinen P, Gläsker S, Bespalov M, Hanski L, Wennerberg K, et al. Discovery
244. Norling LV, Serhan CN. Profiling in resolving inflammatory exudates identifies novel anti- of berberine, abamectin and ivermectin as antivirals against chikungunya and other
inflammatory and pro-resolving mediators and signals for termination. J Intern Med. 2010 alphaviruses. Antiviral Res. 2016 Feb;126:117-24.
Jul;268(1):15-24. 276. Shin HB, Choi MS, Yi CM, Lee J, Kim NJ, Inn KS. Inhibition of respiratory syncytial virus
245. Serhan CN, Levy BD. Resolvins in inflammation: emergence of the pro-resolving replication and virus-induced p38 kinase activity by berberine. Int Immunopharmacol.
superfamily of mediators. J Clin Invest. 2018 Jul 2;128(7):2657-2669. 2015 Jul;27(1):65-8.
246. Lopategi A, Flores-Costa R, Rius B, López-Vicario C, Alcaraz-Quiles J, Titos E, Clària J. 277. Dai Q, Zhang D, Yu H, Xie W, Xin R, Wang L, et al. Berberine Restricts Coxsackievirus B
Frontline Science: Specialized proresolving lipid mediators inhibit the priming and Type 3 Replication via Inhibition of c-Jun N-Terminal Kinase (JNK) and p38 MAPK
activation of the macrophage NLRP3 inflammasome. J Leukoc Biol. 2019 Jan;105(1):25-36. Activation In Vitro. Med Sci Monit. 2017 Mar 25;23:1448-1455.
247. Luo H, Tang QL, Shang YX, Liang SB, Yang M, Robinson N, Liu JP. Can Chinese Medicine 278. Wang YX, Yang L, Wang HQ, Zhao XQ, Liu T, Li YH, et al. Synthesis and Evolution of
Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Berberine Derivatives as a New Class of Antiviral Agents against Enterovirus 71 through
Classics, Research Evidence and Current Prevention Programs. Chin J Integr Med. 2020 the MEK/ERK Pathway and Autophagy. Molecules. 2018 Aug 20;23(8). pii: E2084.
Apr;26(4):243-250. 279. Wu Y, Li JQ, Kim YJ, Wu J, Wang Q, Hao Y. In vivo and in vitro antiviral effects of berberine
248. Ding Y, Chen L, Wu W, Yang J, Yang Z, Liu S. Andrographolide inhibits influenza A virus- on influenza virus. Chin J Integr Med. 2011 Jun;17(6):444-52.
induced inflammation in a murine model through NF-κB and JAK-STAT signaling 280. Enkhtaivan G, Kim DH, Park GS, Pandurangan M, Nicholas DA, Moon SH, et al.
pathway. Microbes Infect. 2017 Dec;19(12):605-615. Berberine-piperazine conjugates as potent influenza neuraminidase blocker. Int J Biol
249. Panraksa P, Ramphan S, Khongwichit S, Smith DR. Activity of andrographolide against Macromol. 2018 Nov;119:1204-1210.
dengue virus. Antiviral Res. 2017 Mar;139:69-78. 281. Lee BH, Chathuranga K, Uddin MB, Weeratunga P, Kim MS, Cho WK. Coptidis Rhizoma
250. Li F, Lee EM, Sun X, Wang D, Tang H, Zhou GC. Design, synthesis and discovery of extract inhibits replication of respiratory syncytial virus in vitro and in vivo by inducing
andrographolide derivatives against Zika virus infection. Eur J Med Chem. 2020 Feb antiviral state. J Microbiol. 2017 Jun;55(6):488-498.
1;187:111925.
30 Integrative Medicine • Vol. 19, No. S1 • Epub Ahead of Print Yanuck—Immuno-physiological Approach to COVID-19