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strongly recommends that these should be begun at first SARS. 11-12 The IV Vitamin C dose regimen recommended
sign of the virus. Period. Many of the arguments against by Dr. Klinghardt is 7.5-50 gm IV daily for 3 days.
this in the media (including medical media) are coming So this is a time for caution rather than fear. Follow
from the illness becoming politicized. the recommendations for social distancing, handwashing,
Although the human research was done in a number of etc. Then turn off the “news” which is giving misinformation
non-placebo-controlled small studies, and reported case grossly out of perspective, to scare people so they watch all
series, they were reasonably well done, include ~ 1000 cases, day. Watching five minutes a day will be enough to learn
and show that combining these two treatments caused 83 % what you need to know.
of people to be virus free after three days and 100% at five So relax, enjoy the time with yourself and your family,
days (versus 19% in the control group), instead of the usual and do the things above to help you and those who treat
20 days. It also made the illness much less severe in both stay safe. You’re going to be OK.
6,7
the French study combining Plaquenil and Zithromax 6, as
well as in the Chinese Plaquenil study. References
8
Preliminary reports from the Chinese authorities 1. Los Angeles Times. 2020. Why This Nobel Laureate Predicts A Quicker
suggests that approximately 100 infected patients treated Coronavirus Recovery: 'We're Going To Be Fine'. [online] Available at:
<https://www.latimes.com/science/story/2020-03-22/coronavirus-outbreak-
with chloroquine experienced a more rapid improvement nobel-laureate> [Accessed 25 March 2020].
in fever and lung CT scan changes, and recovered more 2. Wang D, Ju XL, Xie F, et al. Zhonghua Er Ke Za Zhi. 2020;58(4):E011.
doi:10.3760/cma.j.cn112140-20200225-00138
quickly than the control groups. There were no obvious 3. Ludvigsson JF. Systematic review of COVID-19 in children show milder cases
serious adverse effects. A recent randomized Chinese and a better prognosis than adults [published online ahead of print, 2020 Mar
23]. Acta Paediatr. 2020;10.1111/apa.15270. doi:10.1111/apa.15270
study of 64 cases showed significant benefits as well, with 4. Zhang, L. and Liu, Y., 2020. Potential interventions for novel coronavirus in
faster recovery. All 4 of the patients who progressed to China: A systematic review. Journal of Medical Virology, 92(5), pp.479-490.
severe illness were in the control group. 9 5. te Velthuis AJW, van den Worm SHE, Sims AC, Baric RS, Snijder EJ, et al.
(2010) Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity
Because of this, the Chinese medical advisory board In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell
has suggested chloroquine inclusion in the COVID-19 Culture. PLOS Pathogens 6(11): e1001176. https://doi.org/10.1371/journal.
ppat.1001176
treatment guidelines. 6. Medscape. COVID-19: Could Hydroxychloroquine Really Be An Answer?
In vitro studies also suggest hydroxychloroquine Available at https://www.medscape.com/viewarticle/927033/.
(Plaquenil) to be highly effective against COVID 19. The 7. Gautret P, Lagier J, Parola P, Thuan Hoang V, Meddeb L, Mailhe M, Doudier
10
B, Courjon J, Giordanengo V, Esteves Vieira V, Tissot Dupont H, Honoré S,
entire treatment costs about $20, and is much safer than Colson P, Chabrière E, La Scola B, Rolain J, Brouqui P, Raoult D.
ibuprofen or acid blockers. You may be hearing scare stuff Hydroxychloroquine and azithromycin as a treatment of COVID-19: results
of an open-label non-randomized clinical trial. International Journal of
in the media about visual damage in the retina and other Antimicrobial Agents. 2020. doi: https://doi.org/10.1016/j.
ijantimicag.2020.105949.
problems from the Plaquenil. When you see people saying 8. Devaux CA, Rolain J, Colson P, Raoult D. New insights on the antiviral effects
this, you can know right away that they have no familiarity of chloroquine against coronavirus: what to expect for COVID-19?
with the science or no interest in being accurate. For International Journal of Antimicrobial Agents. 2020. doi:https://doi.
org/10.1016/j.ijantimicag.2020.105938.
example, generally the eye changes do not occur unless one 9. Xueting Yao, Fei Ye, Miao Zhang, Cheng Cui, Baoying Huang, Peihua Niu, Xu
is taking it for over five years. I have seen no reported cases Liu, Li Zhao, Erdan Dong, Chunli Song, Siyan Zhan, Roujian Lu, Haiyan Li,
of significant eye changes or cardiomyopathy with a six day Wenjie Tan, Dongyang Liu, In Vitro Antiviral Activity and Projection of
Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe
course of treatment. Except for occasional stomach upset, Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Clinical Infectious
Diseases, , ciaa237, https://doi.org/10.1093/cid/ciaa237
this treatment is incredibly safe. Knowing this can help you 10. Fiore C, Eisenhut M, Krausse R, et al. Antiviral effects of Glycyrrhiza species.
separate the sense from the nonsense in what you read. Phytother Res. 2008;22(2):141–148. doi:10.1002/ptr.2295
11. Hoever G, Baltina L, Michaelis M, Kondratenko R, Baltina L, Tolstikov GA,
Doerr HW, Cinatl Jr J. Antiviral Activity of Glycyrrhizic Acid Derivatives
Dosing Plaquenil and Zithromax against SARS-Coronavirus. J. Med. Chem. 2005;(48):1256-1259
Although right now the pharmacies are largely sold 12. Ray WA, Murray KT, Hall K, Arbogast PG, Stein CM. Azithromycin and the
out of the Plaquenil, major efforts are being made to make risk of cardiovascular death. N Engl J Med. 2012;366(20):1881–1890.
doi:10.1056/NEJMoa1003833
this available again. The dosing that I recommend is
Plaquenil 200 mg, two tablets twice a day for the first day,
and then one tablet twice a day for five days. The full
treatment is a total of 14 pills over five days. The Zithromax
250 mg dosing would be two tablets the first day, and then
one a day for four days (1 Z pack). It is incredibly easy, low
cost, and safe. I recommend taking both of them together
at first sign of having the infection.

IV vitamin C and glycyrrhizin
For those of you doing IV infusions, both of these I
think are warranted for acute infections. Glycyrrhizin has
been shown to be active against coronavirus, including

14 Integrative Medicine • Vol. 19, No. 2 • April 2020 Teitelbaum—COVID 19